ODCs

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6 OMIM references -
5 associated genes
9 signs/symptoms

PROTEIN INTERACTIONS: 1

1 associated gene
No signs/symptoms info

Split hand-split foot malformation

Familial adenomatous polyposis due to 5q22.2 microdeletion


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	BTRC	(0.87)	APC

Citations in the biomedical literature:

Split hand-split foot malformation		Familial adenomatous polyposis due to 5q22.2 microdeletion
	Synonym(s): - Ectrodactyly - Lobster-claw deformity - SHFM - Split hand foot malformation		Synonym(s): - Colorectal adenomatous polyposis due to monosomy 5q22.2 - FAP due to monosomy 5q22.2 - Familial adenomatous polyposis due to del(5)(q22.2) - Familial adenomatous polyposis due to monosomy 5q22.2 - Familial polyposis coli due to monosomy 5q22.2

	Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare gastroenterologic disease - Rare genetic disease - Rare oncologic disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: (no data available)

	External references: 6 OMIM references - No MeSH references		External references: No OMIM references No MeSH references

Split hand-split foot malformation
	Very frequent - Autosomal dominant inheritance - Oligodactyly / ectrodactyly of fingers Frequent - Syndactyly of fingers / interdigital palm Occasional - Aniridia / iris hypoplasia - Autosomal recessive inheritance - Hand agenesis / absence - Sensorineural deafness / hearing loss - Trident hand / split hand / abnormal median ray - X-linked recessive inheritance
Familial adenomatous polyposis due to 5q22.2 microdeletion
(no data available)